One-pot synthesis of template-free hollow anisotropic CaCO3 structures: towards inorganic shape-mimicking drug delivery systems

Authors: Serov N.S.Darmoroz D.D., Lokteva A. V., Chernyshov I.Y., Koshel E.I., Vinogradov V.V.

Abstract

A major obstacle in the introduction of nanoformulated drugs has been the fact that the shape of the drug delivery systems (DDSs) – the most important parameter driven by the nature of viruses and bacteria – remains almost out-of-scope in artificial systems. Here we propose a potential solution for this problem by developing a template-free approach for the formulation of hollow bacteria-like CaCO3-based pH-sensitive DDSs with controllable anisotropy and click-release behavior.

DOI: 10.1039/D0CC05502F 

Read full: https://pubs.rsc.org/en/content/articlehtml/2020/cc/d0cc05502f