Authors: Gorbenko D.A., Shkodenko L.A., Rubel M.S., Slita A.V., Nikitina E.V., Martens E.A., Kolpashchikov D.M.
Visual detection of ssRNA and dsDNA amplicons was achieved at room temperature without the need for a probe-analyte annealing stage. This approach uses a DNA nanostructure equipped with two analyte-binding arms. Highly selective binding of the third arm leads to the formation of a G-quadruplex structure capable of changing the solution color.
