«Molecular Biology and Biotechnology» program aims at the preparation of high-qualified specialists in the fields of new methods for diagnostics and treatment, drug delivery, nanodevices and materials with new properties. This program is made for those who want to do world-level science during the master study.
The program uses an innovational interdisciplinary approach, combining modern information technologies and state-of-art practical methods. The program is based on a synergy of experiment and modelling in a cell, molecular- and microbiology and biochemistry.
The practical part is supported by theoretical courses form the leading scientists who specialize in the fields of molecular biology, oncology, new materials for biomedical applications, marketing of new technologies, etc.
You can perform a research project in one of the research groups or work on your own startup in an industrial laboratory. Depending on your project from the second semester, you choose an individual educational trajectory in one of the following specializations:
This program includes modern trends in the field of biology and biotechnology.
The first specialization is cell biology. As part of this specialization, projects are being carried out in the field of cell (the study of the behavioral characteristics of cells in the presence of nanopharmaceuticals or nanoparticles, as well as apoptosis - programmed death of cancer cells) or microbiology (programming and control of biofilms and nanotechnology in microbiology).
The second specialization is molecular biology. This specialization deals with projects related to DNA structures for the treatment of various diseases, sensors and systems for the diagnosis of infectious diseases.
The third specialization is nanopharmaceuticals. Within this framework, approaches for obtaining promising materials, methods of nanoformation of drugs, preclinical research, in other words, a full cycle: from research to experimental design, preclinical research and clinical trials are considered.
Research groups: nanopharmaceuticals (Vladimir Vinogradov), infochemistry of self-organizing systems (Ekaterina Skorb), experimental oncology (Alexander Shtil), ceramic and natural nanomaterials (Pavel Krivoshapkin).
The fourth specialization is the industrial brokerage in the field of biotechnology. In this direction, competencies are developed not only in the field of biology and biotechnology but also in the field of economics and finance, innovation and innovation. The projects are based on the fact that the products developed in the previous stages have access to real commercial startups, patents - that is, everything related to further commercialization.
Industrial laboratory, in cooperation with all research groups.
What kind of specialists do we teach?
Educational and scientific components are built in such a way as not to sharpen the system for a particular enterprise or research direction in connection with constantly changing leading enterprises, industries, markets. Our task is to prepare competitive specialists who are able to solve non-standard tasks, implement non-standard projects, bring them to commercialization, and by the end of the magistracy our graduates have professional and interdisciplinary skills and an excellent portfolio.
The course combines specific elements of spoken English (presentation skills, professional immersion) and academic English (critical and analytical thinking, academic writing).
The main topics of this course include DNA replication, transcription, translation and DNA repair, as well as the fundamentals of molecular biology.
This course provides an interdisciplinary approach to understanding the outside world and the creation of materials that chemically “speak” to living cells; Reproduces the mechanism of self-organizing “smart” technologies;explains diffusion-limited growth models, percolation theory, and adaptive evolution using analogies; describes time dependencies, oscillations, autocatalysis and system feedback, features of spontaneous synthetic and biocatalytic processes; reproduces graphical methods for describing model dynamics.
Today, highly effective molecular biology and bioengineering is impossible without the implementation of bioinformatics. This course covers the main topics of bioinformatics with a detailed explanation of the structural bioinformatics of proteins; molecular modeling; molecular docking and evaluation; and databases and software.
This course explains the effectiveness of nanomedicine, including technologies for producing materials from microbiological synthesis; includes a description of the main methods for the study of biological metabolites and macromolecules, and molecular diagnostic methods; reveals the theoretical and applied aspects of the use of nanostructured materials for biomedicine purposes (genomics, proteomics, genetic engineering, biomaterial science and modern analytics).
This course focuses on the main technologies for the production of recombinant DNA, RNA, gene knockouts; and approaches for visualizing gene expression. The latest methods of gene manipulation will also be considered.
This course describes the fundamentals of preclinical studies, namely GLP, GCP, and pharmacokinetic parameters; aims to teach the principles of writing reports on preclinical studies, legal compliance and standards governing conduct; highlights phases of clinical trials; substantiates research methods for acute and chronic toxicity, as well as specific toxicity; describes test systems for studying the effectiveness of drugs, and the stages of planning a preclinical experiment.
This course highlights the fundamentals of synthesizing nanoparticles with various composition and morphology; describes the main methods of research and prediction of toxicity of nanoparticles in vitro models; aims to conduct cytotoxicological experiments, organize and control preclinical studies of drugs and clinical trials of drugs; substantiates the use of nanoparticles in biomedicine, and current trends in their use in the pharmaceutical industry.
This course covers the most important aspects of creating modern biological and molecular sensors, including the use of antibodies for laboratory and medical analyses; biological receptors and the concept of artificial nose; enzyme/substrate interactions and enzymatic sensory systems; nucleic acid probes, molecular beacons, Tuckman samples, deoxyribozymes , apta-sensors, and bioelectrosensors.
This course teaches the fundamentals of molecular oncology; describes the main molecular signs of cancer, changes in the metabolism of the tumor cell, and changes to the immune system due to cancer; conveys methods for studying the cell cycle, apoptosis, intracellular signal transmission, mechanisms for regulating the cell cycle, mechanisms of invasion, metastasis, and angiogenesis; is aimed at teaching methods of tumor cell analysis - immunoblotting, flow cytometry, analysis of the effectiveness of the production of targeted drugs and cell cycle inhibitors.
The goal of this course is to refresh and deepen knowledge of classical biochemistry and use it to analyze the most important discoveries that have won the Nobel Prize as well as the latest biochemical developments, including DNA nanotechnology, synthetic biology, epigenetics, RNA visualization in cells, CRISPR, and high throughput DNA sequencing.
During the course, you will study the structure and functions of natural protein machines, myosin, kinesin and dynein, as well as modern achievements in the field of creating an artificial molecular machine for biomedical applications.
This course includes a description of the methods of stabilization and regeneration of enzymatic systems used in biotechnology; provides an understanding of the structural foundations of protein function and the thermodynamic foundations of the functioning of enzymes in extreme conditions; is focused on predicting the results of the influence of exogenous and endogenous environmental factors on the molecular genetic organization of proteins; describes the fundamental and applied aspects of structural and functional proteomics, and examples of the use of biocatalysts in science, medicine, technology, and industry.
The course provides the fundamentals of comparative and evolutionary molecular neuroscience; highlights neurophysiological mechanisms for the implementation of cognitive functions, the molecular mechanisms of interneuronal interactions, and current methods of studying neuropsychophysiological states; briefly describes the main facilities and apparatuses used to solve research problems in the field of molecular neuroscience; describes the structure and principles of neuronal membrane function, especially proteins, lipids and energy in the central nervous system.
This course includes the following sections: historical moments in nanobiotechnology development; a brief overview of current applications and approaches in the use of nanobiotechnology, modern materials for nanobiotechnology, the biological characterization of materials, molecular mechanisms of the cellular antioxidant system, molecular aspects of the nervous function, and nanobiosensors.
Students will learn the fundamentals and role of information in the development of modern society; basic principles of collecting and preparing raw data; basic methods of data analysis; the stages and technology of software development for solving data processing problems; to use mathematical tools for processing, analyzing and systematizing information on the research topic. Students will study remove basic methods of data collection and tools for information processing; factor and cluster analysis skills; data processing methods; and design and automated system operation skills.
This course contains a description of the life cycle stages of the designed or studied research objects in the field of nanostructured materials. It is designed to analyze the economic, environmental, and social restrictions of nano-object and nanomaterial production; tracks current trends in nanoparticle use as well as current nanostructure standardization and certification methods; includes a description of modern methods for producing catalysts and functional coatings, their characterization, development of technological lines and the integration of science and business.
As part of the course, you will consider the following sections: types of projects; the uniqueness of a startup as a project; project evaluation; features of a startup assessment; project risk assessment and start-up. You will also get acquainted with project management in the professional field: international project, examples of successful projects; project management technology; the use of the latest information systems in the project management process; project effectiveness assessment.
This course includes the following sections: an introduction to forecasting; modern practices for forecasting the development of global markets; global challenges; forecasting methods for the scientific and technological development and global markets; planning research and development on forecast basis; the analysis of global market forecasts in the field of bioengineering.
As part of the course, you will learn to evaluate the readiness of technology (product or service) to enter foreign markets, learn international business practices, and analyze successful practices of modern entrepreneurs. You will also be trained to analyze markets, conduct competitive analysis, work with unions and entrepreneurial associations. The course includes security issues, international intellectual property, intellectual property as a product, and the assessment of intellectual property protection capabilities. You will be taught the first steps of business, namely how to register a company and interact with banks, local authorities, and the business community.
This course will immerse students in analytical data processing methods, and the basics of artificial intelligence. It will teach the utilisation of digital technologies, including software products, in everyday life and in the professional field. Students will master core information retrieval technologies and data processing, analysis and protection technologies, as well as modern tools and computer technologies for solving problems associated with data processing and analysis, in relation to any subject area.
This course is delivered by the experts, active in various fields of fundamental and applied research; scientists with the background in top world’s universities and research corporations (Tsinghua University, National Research University Higher School of Economics, Harvard Business School and others).
Internationalization of research course will provide you with the tools that help us organize ourselves in research environment, build a research team or become a part of one successfully, choose suitable research methods, share your findings with the scientists in an oral or written form (presentation skills), present your research or pitch your ideas to the investors. You will be able to write a decent resume, take the most of a multicultural environment, learn scientific reference management, know how to write a scientific paper, locate funding to scaffold your research (apply for grants) and perform effectively in business communication. In a nutshell, this course will teach you everything that an aspiring researcher needs to know to be successful.
Professor of the University of Central Florida (Orlando, USA), Professor at ITMO University, Head of Molecular Robotics and Biosensor Materials SCAMT Laboratory
Courses: Molecular Biology, Molecular biorobotics, Fundamentals of genetic engineering
Dmitry is a specialist in the field of nucleic acid biochemistry, molecular diagnostics and DNA nanotechnology.
From 2003 to 2008 he worked at the University of Colombia (New York, USA) since 2008 he has been working at the University of Central Florida (Orlando, USA)
He is the author of more than 70 publications and winner of various awards of scientific communities in Japan, the USA, and Russia.
His research interests include nucleic acid-based biosensors, bioorganic chemistry (irreversible inhibition, nucleic acid biochemistry, structural and dynamic aspects of protein-ligand interaction, protein and nucleic acid cross-linking), synthetic biology (structural DNA-nanotechnology, logic circuits, biomolecular engineering).
Professor of ITMO University, Head of the group Infochemistry of self-organizing systems SCAMT laboratory.
Course: Molecularly organized systems
Ekaterina is a specialist in the field of physical chemistry of heterostructures and nanomaterials.
Since 2008, she worked at the Institute of Colloids and Interfaces named after him. Max Planck (Potsdam, Germany), and since 2016 she has been a professor at Harvard University (USA).
Author of more than 60 publications and various fellows (AvH, DAAD, LG Chem, etc.)
Professor of the ITMO University, Head of the Laboratory of Bioinformatics of the ITMO University
Worked at Saratov City Medical University, Department of Physiology and Pharmacology, University of Tel Aviv (Israel), Laboratory of Molecular Biology, Istituto di Fisiologia Clinica del CNR, (Pisa, Italy
Course: Molecular Oncology
Graduated from the Department of Cell Biology and Histology at the Biological Faculty of Moscow State University.
In 2010 he defended his thesis on the topic: "The mechanisms of tumor cell death under the action of new carbohydrate derivatives of indolocarbazoles", in the specialty "oncology". Since 2005, he has been working in the laboratory of tumor cell death mechanisms at the Research Institute of Carcinogenesis of the NNRRCRC. Blokhin. In 2006-2007 he worked at the Karolinska University.
Research interests: programmed tumor cell death, cell cycle regulation, molecular oncology, DNA damage.
Researcher at SCAMT laboratory
Course: Advanced Materials for Biomedical Applications
The author of twenty articles, the owner of two patents.
Professor of ITMO University, the group leader of Microbiology laboratory SCAMT.
Courses: Methods in nanomedicine, Tissue engineering
Elena is a specialist in microbiology.
From 2015 to 2018 she worked as a postdoc at St. Petersburg State University. Author of more than 30 publications.
Researcher of the laboratory SCAMT.
Course: Preclinical Studies
SCAMT postdoc, PhD
Arthur is a specialist in bionanotechnology.
More than 20 publications in collections and materials of conferences of the Russian and international level. He participated in the implementation of more than 9 different grants of the Russian Foundation for Basic Research, the Russian National Science Foundation, the President of the Russian Federation.