Effect of Sol–Gel Alumina Biocomposite on the Viability and Morphology of Dermal Human Fibroblast Cells

Authors: Iglin V.A.Sokolovskaya O., Morozova S.M., Kuchur О.А., V.G. Nikonorova, Sharsheeva A., Chrishtop V.V., Vinogradov A.V.


This paper is the continuation of our previous work on the ability of biocomposites based on sol–gel alumina (boehmite) to promote skin recovery from burns and atrophic scars. The present study describes the increasing of the cytoplasma volume and the number of filopodias of HDF cells, which for the first time indicates their proliferation on the alumina itself and on alumina-based biocomposite. Studies in vivo confirm the efficiency of the composite in the treatment of atrophic scars.


Read Full: https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c00721